Electrical impedance-based microfluidics systems offer many advantages over alternative techniques: they are label-free, non-invasive, and faster than camera-based systems. Measurements can be taken at multiple frequencies to give an impedance profile of the object under test for enhanced selectability. For example, cells flowing in a fluid, microplastics, or even the level of fluid mixing or properties of the fluid such as the pH value. All this can be done non-destructively and in real-time to allow for fast data acquisition and immediate decision making.
The HF2LI 50 MHz Lock-in Amplifier brought this functionality to microfluidics back in 2008. Now, Zurich Instruments is continuing to innovate in this area, allowing you to take your microfluidics system into the GHz regime to improve sensitivity and increase selectability.
Zurich Instruments offers an innovative solution for microwave microfluidics with our microwave lock-in amplifiers: the SHFLI 8.5 GHz Lock-in Amplifier and the GHFLI 1.8 GHz Lock-in Amplifier. Both instruments offer fast measurement of the dielectric signal as the object under test passes the electrodes or resonator sensor.
To improve the selectability of your measurements, the SHFLI and GHFLI offer characterization at multiple frequencies simultaneously from DC to 8.5 GHz, so you can distinguish your cells and objects with confidence, enabling real-time decision making and bringing peace of mind thanks to multi-frequency profiling.
To learn more about how the SHFLI and GHFLI can enable new levels of sensitivity and flexibility, get in touch to set up a call with our application specialist in your region. In addition to microwave microfluidics, here’s a list of resources to show your research can benefit from the capabilities of our instruments.
A sensor generates an electrical signal that depends on the physical quantity we aim to measure. Achieving the desired performance is an iterative process that begins with finding suitable materials, sensing methods, and control parameters. A complete toolset to characterize the prototype with efficient workflows is crucial to keep up with the project timelines. In this webinar, Kıvanç Esat and Jim Phillips present the measurement requirements, discuss the essential tools, and explain best practices with examples to accelerate your testing.
Find out how Zurich Instruments' users are boosting their measurements.
A lock-in amplifier offers a convenient way to measure impedance in a continuous flow of water. We can use the impedance change to tell the difference between biological particles - which we hope to see in abundance - and microplastics.
Beckett Colson and Dr. Anna Michel
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